How to live with Bipolar Disorder. Some secrets of bipolar disorder treatment

Bipolar disorder is a kind of mental illness manifesting itself in cyclic mood shifts. In most cases, the disease results in mood swinging from euphoria to depression and vice versa. These mood shifts are often dramatic, and without due treatment episodes may result in severe outbreaks of aggression or suicidal behavior.

Major depressive disorder: reasons, symptoms, ways of recovering.

Lots of doctors of our century and previous years  have been bothering their heads about what major depressive disorder is and how to prevent it. In most materials a person with such an illness is described as sad, unhappy and very miserable. Many people go through it in one or another period of lifetime.  Major depressive disorder (clinical depression) is a mental and mood disorder in which feelings of frustration, anger and sadness interfere everyday life for weeks or even longer.

Patients with affective disorders

The PCA was performed on groups 1, 2 and 3, which contained scored clinical bipolar disorder symptoms , together with the three biolog­ical variables, platelet monoamine oxidase (MAO) serum melatonin and post-dexamethasone serum cortisol. 

Identification of patients with latent bipolar disorder

The operational criteria for the diagnosis depression is based on categorical and/or quantitative variables. A sub­type of depression, affective psychosis, is characterised by genetic vulnerability and a positive clinical bipolar disorder treatment.

Hypomania as a form of manic disorders

Normal human beings show marked mood fluctuations and obviously there is a continuum from sustained ela­tion to mildly pathological states or traits. This has been frequently maintained in the literature, for instance, by Jung (1904), Schneider (1932), Wertham (1929a, b), and more recently by Kendell (1985). As early as 1910 Reiss had stressed that every distinction between normal and pathological mood is to a certain extent artificial.

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Diagnostic efficiency and bipolar disorder test

In pursuing the validity of individual bipolar disorder symptoms, these methods eschew the demonstration of statistically different criteria rates between diagnostic groups, because such differences will hold for symptoms that are not useful for the diagnostician. Instead, the focus is on a conditional prob­ability analysis which computes the sensitivity, specific­ity, positive predictive power and negative predictive power symptoms of bipolar disorder and combinations of symptoms of bipolar disorder as predictors of diagnoses. 

Methods that define symptoms of bipolar disorder

One of methods moves one step closer to a true psychiatric genetic nosology. Instead of using pre­defined categories, these methods attempt to define new phenotypes that maximally correspond to the genetic component of bipolar disorder symptoms

Methods for psychiatric genetic nosology of bipolar disorder treatment

Variable expression appears to be a common feature of familial psychiatric bipolar disorder treatment. The schizophrenia ge­notype may produce schizoaffective disorder, schizotypal personality and atypical psychotic disorders. The biological relatives of bipolar patients are at high risk for major depressive and bipolar II disorders

Identification of the bipolar disorder symptoms

A century of research into the genetic basis of psycho­pathology has opened new vistas for research and new hopes for bipolar disorder treatment. For many psychiatric disorders we have a sturdy foundation of genetic epidemiological data that posits genes as etiological. 

Bipolar disorder symptoms

Bipolar disorder is a mental condition, which presents in radical mood shifts. Commonly, patients have to pass through periods of elevated mood (mania) alternating with depression.

Implications for Affective Disorders

There is now mounting evidence that the pathophysio­logy of melancholia and the mechanism of action of anti­depressive treatments involve both alterations in circa­dian rhythms as well as changes in central noradrenergic sen­sitivity.

Major depression disorder and syndromes

Obsessive-compulsive symptoms frequently occur in the general population and are fundamental features of ob­sessive-compulsive personalities. Obsessive-compulsive disorder (OCD), characterized by high chronicity, how­ever, is considered a rare psychiatric disorder. 

Episodes of Major Depressive Disorder

A first major depressive episode (MDE) that does not recur during follow-up has been reported to be relatively uncommon. Thus, at the first episode, the clinician is expected to assess which disorder (recurrent unipolar or bipolar) the depressive episode will ultimately belong to. 

Lithium and carbamazepine as the maintenance treatment of bipolar disorder

When separately evaluating patients with "Bipolar Disorder" according to DSM- III-R and the group of patients with heterogeneous disorders such as “Bipolar Disorder NOS", “Major Depression”, “Schizophrenia”, “Schizophreniform Disorder", “Schizo-affective Disorder" and “Psychotic Disorder NOS", again the results support the hypothesis of a different treatment response.

Comparison of Bipolar and Unipolar depression

Using the terms “unipolar diseases” and “bipolar diseases” instead of “affective disorders” or “schizoaffective disorders” would make sense only if the well-known differences between unipolar and bipolar affective disorders and unipolar and bipolar schizoaffective disorders still remain after building these two voluminous groups and if they can clearly be separated on several levels. 

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